Biofabrication: 3D Printing for Tissue Engineering
Weng Kwan, Michael
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Biofabrication is the use of additive manufacturing (3D printing) for biological applications. The ultimate goal of biofabrication is to print viable organs for transplantation using patients’ own cells. In order for successful transplantation, printed organs must be made of living cells and incorporate functional vasculature. Therefore, the main goal of this design is to print a 3D structure of living tissue with an integrated vascular network capable of perfusion using a reproducible process. This is accomplished by building a tissue incubation chamber to maintain sample integrity during the printing process, developing an extrusion-based printing method that utilizes multiple bioinks to produce the bulk tissue and vascular tubes, and applying a unique method of alternating current (AC) electrospinning to create an integrated capillary-like network .