dc.contributor.advisor | Brenner, James | |
dc.contributor.author | Melegrito, Jonah Martin | |
dc.date.accessioned | 2019-09-23T14:35:44Z | |
dc.date.available | 2019-09-23T14:35:44Z | |
dc.date.created | 2019-05 | |
dc.date.issued | 2019-05 | |
dc.date.submitted | May 2019 | |
dc.identifier.uri | http://hdl.handle.net/11141/2914 | |
dc.description | Thesis (M.S.) - Florida Institute of Technology, 2019. | en_US |
dc.description.abstract | As a cell line thrives within a culture, some of the cells undergo the natural process
of death. Whether it is due to apoptotic or necrotic causes, cell death is a significant
hurdle for tissue engineering and cell cultivation. When cells attached to a scaffold
die, they slough off from the scaffold into the bloodstream. If left unchecked, these
dead cells and any cellular waste products accumulate and could affect the living
cells’ ability to survive. The objective of this thesis was to construct a separation
system that can filter away any unwanted suspended solids while allowing nutrients
to recycle back into the bioreactor. The capacity of the filters used in this separation
system was determined by utilizing a resistance-in-series model. The upper limit of
control variables for operation such as pressure drop and turbidity for the filters is
also established in this thesis. | en_US |
dc.format.mimetype | application/pdf | |
dc.language.iso | en_US | en_US |
dc.rights | Copyright held by author. | en_US |
dc.title | Validation of an External Bioreactor Filtration Loop Prototype for a Tissue Engineering Test Bed | en_US |
dc.type | Thesis | en_US |
dc.date.updated | 2019-08-20T14:39:46Z | |
thesis.degree.name | Master of Science in Chemical Engineering | en_US |
thesis.degree.level | Masters | en_US |
thesis.degree.discipline | Chemical Engineering | en_US |
thesis.degree.department | Biomedical and Chemical Engineering and Sciences | en_US |
thesis.degree.grantor | Florida Institute of Technology | en_US |
dc.type.material | text | |