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dc.contributor.advisorBrenner, James
dc.contributor.authorMelegrito, Jonah Martin
dc.date.accessioned2019-09-23T14:35:44Z
dc.date.available2019-09-23T14:35:44Z
dc.date.created2019-05
dc.date.issued2019-05
dc.date.submittedMay 2019
dc.identifier.urihttp://hdl.handle.net/11141/2914
dc.descriptionThesis (M.S.) - Florida Institute of Technology, 2019.en_US
dc.description.abstractAs a cell line thrives within a culture, some of the cells undergo the natural process of death. Whether it is due to apoptotic or necrotic causes, cell death is a significant hurdle for tissue engineering and cell cultivation. When cells attached to a scaffold die, they slough off from the scaffold into the bloodstream. If left unchecked, these dead cells and any cellular waste products accumulate and could affect the living cells’ ability to survive. The objective of this thesis was to construct a separation system that can filter away any unwanted suspended solids while allowing nutrients to recycle back into the bioreactor. The capacity of the filters used in this separation system was determined by utilizing a resistance-in-series model. The upper limit of control variables for operation such as pressure drop and turbidity for the filters is also established in this thesis.en_US
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen_US
dc.rightsCopyright held by author.en_US
dc.titleValidation of an External Bioreactor Filtration Loop Prototype for a Tissue Engineering Test Beden_US
dc.typeThesisen_US
dc.date.updated2019-08-20T14:39:46Z
thesis.degree.nameMaster of Science in Chemical Engineeringen_US
thesis.degree.levelMastersen_US
thesis.degree.disciplineChemical Engineeringen_US
thesis.degree.departmentBiomedical and Chemical Engineering and Sciencesen_US
thesis.degree.grantorFlorida Institute of Technologyen_US
dc.type.materialtext


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