Browsing College of Engineering and Science by Author "Lakshmana, Madepalli Krishnappa"

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RanBP9 overexpression accelerates loss of pre and postsynaptic proteins in the APΔE9 transgenic mouse brain

Wang, Hongjie; Wang, Ruizhi; Xu, Shaohua; Lakshmana, Madepalli Krishnappa (2014-01-14)

There is now compelling evidence that the neurodegenerative process in Alzheimer's disease (AD) begins in synapses. Loss of synaptic proteins and functional synapses in the amyloid precursor protein (APP) transgenic mouse ...