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dc.contributor.authorFu, Linglin
dc.contributor.authorYan, Xuxia
dc.contributor.authorRuan, Xinming
dc.contributor.authorLin, Junda
dc.contributor.authorWang, Yanbo
dc.identifier.citationFu, L., Yan, X., Ruan, X., Lin, J., Wang, Y. Differential protein expression of Caco-2 cells treated with selenium nanoparticles compared with sodium selenite and selenomethionine (2014) Nanoscale Research Letters, 9 (1), 9 p. Cited 3 times.en_US
dc.descriptionProteomics, Selenium nanoparticle, Selenomethionine, Sodium seleniteen_US
dc.description.abstractThe study was designed to determine the differential protein expression of Caco-2 cells treated with different forms of selenium including sodium selenite, selenomethionine (Se-Met), and selenium nanoparticles (nano-Se). Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and mass spectrometry (MS) were used to identify the differentially expressed proteins. The results indicated that seven protein spots, ubiquitin-conjugating enzyme E2 (E2), glutathione synthetases (GS), triosephosphate isomerase (TSP), T-complex protein 1 subunit zeta (TCPZ), lamin-B1, heterogeneous nuclear ribonucleoprotein F (hnRNP F), and superoxide dismutase [Cu-Zn] (Cu, Zn-SOD) were significantly different among all the groups. According to the order of control, sodium selenite, Se-Met, and Nano-Se, the expression levels of two proteins (E2 and GS) increased and the other differential proteins were reverse. Except for E2, there were no significant differences in other protein expressions between the groups treated with nano-Se and Se-Met.en_US
dc.rights© Fu et al.; licensee Springer. 2014en_US
dc.titleDifferential protein expression of Caco-2 cells treated with selenium nanoparticles compared with sodium selenite and selenomethionineen_US

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© Fu et al.; licensee Springer. 2014
Except where otherwise noted, this item's license is described as © Fu et al.; licensee Springer. 2014