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dc.contributor.authorWaynant, Ronald W.
dc.contributor.authorIlev, Ilko K.
dc.contributor.authorKunal, Mitra
dc.date.accessioned2017-10-03T18:43:20Z
dc.date.available2017-10-03T18:43:20Z
dc.date.issued2001-05-21
dc.identifier.citationWaynant, R. W., Ilev, I. K., & Mitra, K. (2001). Waveguide delivery of x-rays for minimally invasive tumor therapy. Proceedings of SPIE - the International Society for Optical Engineering, 4244, 492-499.en_US
dc.identifier.urihttp://hdl.handle.net/11141/1697
dc.descriptionX-rays, Hollow waveguides, Tumor irradiation, Dosimetry, Minimally invasive therapyen_US
dc.description.abstractWe are studying the potential use of x-rays, which are collected by non-imaging optics and delivered through stereotactically guided needles by hollow waveguides, for irradiation of tumors. X-rays have greater transparency in tissue than most longer optical wavelengths and may provide a more uniform dose to a tumor without harming normal tissue. Dosimetry is the key to minimal damage. We are investigating the use of fiber optics, tipped with calibrated scintillators and strategically located near the tumor, to measure the delivered dose. We are testing this procedure by using a 3 ns, variable accelerator voltage Fexitron 706 to produce approximately 50 mrads of x-ray energy. We concentrate, homogenize and inject this radiation into meter length, submillimeter hollow waveguides. We place the waveguides in a simulated tumor (a phantom breast). Streak and thermal cameras monitor the energy distribution during the irradiation by observing the distribution of energy as evidenced by fluorescence and heat. Once optimum exposure conditions of placement and dose are determined, tissue studies will begin.en_US
dc.language.isoen_USen_US
dc.rightsThis published article is made available in accordance with publishers policy. It may be subject to U.S. copyright law. © (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).en_US
dc.rights.urihttp://spie.org/publications/journals/guidelines-for-authors#Terms_of_Useen_US
dc.titleWaveguide delivery of x-rays for minimally invasive tumor therapyen_US
dc.typeConference Proceedingen_US
dc.identifier.doi10.1117/12.427840


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