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Recent Submissions

  • Developing the Three Dimensional Tumor Model for Melanoma Drug Screening 

    Ye, Guochang (2016-12)
    Two-dimensional (2D) Tissue Culture Treated Plastic (TCTP) is widely used for cancer drug screening and has dominated the field for a long time. Compared with traditional two dimensional cell culture, a three dimensional ...
  • Rapid Generation of 3D Microchannels Using a Multiphoton Laser System in Blended Hydrogels to Serve as Templates for Microvascular Generation 

    Burtch, Stephanie Renée (2016-09)
    Lack of scaffold microvascularization is one of the biggest problems facing graft survival and success within current tissue engineering applications. Fortunately, techniques aiming to form microchannels within ...
  • Assessment of the Correlation between Memory Span Test Result and Attention using a Wireless EEG System 

    Yu, Yu (2016-09)
    The process to encode, retain and retrieve information is known as memory. Ever since models for short-term memory and working memory systems were proposed, the function and importance of the short-term memory and working ...
  • MOTIL™ Monitoring and tracking integrated in life 

    Anthony, Dylan; Bloom, Kristopher; Carlton, Paige; Cushman, Jessica; Dias, Juston; Herschelman, Karley
    An estimated 70% of the population does not walk with correct pronation. Pronation is the method of distributing weight across the plantar surface of the foot. This leads to severe pain and joint damage over time.
  • Solarizer 

    Brandt, Michael; Green, Michael; Pearce, Shelby; Soileau, Liana
    In developing countries and following natural disasters, there is a need for a portable solar powered autoclave to properly sterilize surgical equipment because there is often no access to electricity or natural gas. Without ...
  • PriMA prosthetics –3D printed myoelectric prosthetic arm 

    Brown, Clyde; Berger, Thaddeus; Spagnolo, Austin; Atkinson, Taylor; Pastakia, Meet; Yaman, Zuhoor; Ballman, Nicole; Pavao, Justin; Babbit, Ryan; Goldman, Dannielle; Elena, Maria Vittoria
    Develop an innovative 3D printable prosthetic arm solution which is strong and life-like in appearance and function. The device should meet all FDA standards and be designed for commercialization.
  • Cell Ray 3D Bioprinter 

    Bocinsky, John; Mason, Eric; Weaver, Nevada; Wood, Kristin
    For research of cancer and other diseases,it has become increasingly more important to have accurate 3D culture models that more closely mimic in vivo tissues and the surrounding extracellular matrix (ECM). The current and ...
  • Vasreactor 

    Boeringer, Tabitha; Estacio, Alvin; Hyland, Joan; Theus, Andrea
    Heart disease is the leading cause of death in the United States. There are numerous issues with finding healthy blood vessels in such patients, with them often having to return to surgery due to bypass failure. Bioreactors ...
  • Bio Exo Skulder – The Shoulder Brace 

    McClure, Ian; Kim, Jacob; Mogharbel, Reham; Brito, Carlos
    The shoulder joint is: •A ball-and-socket joint (3 degree of freedom) •Stabilized by the rotator cuff, a group of muscles and tendons •Highly susceptible to injury •Difficult to repair due to its complexity
  • Analyzing & Interpreting Conductive Education A.I.C.E. 

    Cord, Harrison; Kaseman, Sarah; Macias, Jocday; Macias, Jocsan; McFadden, Rebecca; Mogharbel, Rawan; Reynolds, Phillip; Tate, Ariana; Vidas, Anastasios
    Conductive Education is a unique, holistic educational approach to help children with Cerebral Palsy and other motor disabilities achieve their greatest level of independence through physical and cognitive activities. The ...
  • Impact of elastin incorporation into electrochemically aligned collagen fibers on mechanical properties and smooth muscle cell phenotype 

    Nguyen, Thuy-Uyen; Bashur, Chris A.; Kishore, Vipuil (2016-03-17)
    Application of tissue-engineered vascular grafts (TEVGs) for the replacement of small-diameter arteries is limited due to thrombosis and intimal hyperplasia. Previous studies have attempted to address the limitations of ...
  • Theranostic oxygen delivery using Ultrasound and microbubbles 

    Kwan, James J.; Kaya, Mehmet; Borden, Mark A.; Dayton, Paul A. (2012-12-23)
    Means to overcome tumor hypoxia have been the subject of clinical investigations since the 1960’s; however these studies have yet to find a treatment which is widely accepted. It has been known for nearly a century that ...
  • Reference point indentation is not indicative of whole mouse bone measures of stress intensity fracture toughness 

    Carriero, Alessandra; Bruse, Jan L.; Oldknow, Karla J.; Millán, José Luis; Farquharson, Colin; Shefelbine, Sandra J. (2014-10-14)
    Bone fragility is a concern for aged and diseased bone. Measuring bone toughness and understanding fracture properties of the bone are critical for predicting fracture risk associated with age and disease and for preclinical ...
  • Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing 

    Javaheri, Behzad; Carriero, Alessandra; Staines, Katherine Ann Nn; Chang, Y. M.; Houston, D. A.; Oldknow, Karla J.; Millán, José Luis; Kazeruni, Bassir N.; Salmon, Phil L.; Shefelbine, Sandra J. (2015-12-01)
    PHOSPHO1 is one of principal proteins involved in initiating bone matrix mineralisation. Recent studies have found that Phospho1 KO mice ( Phospho1-R74X) display multiple skeletal abnormalities with spontaneous fractures, ...
  • Effects of normal and abnormal loading conditions on morphogenesis of the prenatal hip joint: application to hip dysplasia 

    Giorgi, Mario; Carriero, Alessandra; Shefelbine, Sandra J.; Nowlan, Niamh C. (2015-06-30)
    Joint morphogenesis is an important phase of prenatal joint development during which the opposing cartilaginous rudiments acquire their reciprocal and interlocking shapes. At an early stage of development, the prenatal hip ...
  • Impact of Collagen-Incorporation within Electrospun Vascular Conduits on the Inflammatory Response and Conduit Mechanics 

    Birthare, Karamveer (2015-05)
    Current surgical alternatives for treating coronary artery diseases are limited in patients with systemic vascular diseases due to unavailability of suitable autologous vessels. The overall goal of this research project ...
  • Wheelchair-Mounted Exercise Equipment for Paraplegics 

    Aljohani, Kamal; Enderli, Tanya; Guan, Shan; Hillman, Drake
    According to the National Spinal Cord Injury Statistical Center (NSCISC) there are over 276,000 people living with a spinal cord injury in the United States, and 41% of these injuries are classified as paraplegia. Since ...
  • Biofabrication: 3D Printing for Tissue Engineering 

    Bailey, Ryan; Baskerville, Scott; Gilchrist, Victoria; Weng Kwan, Michael; McClure, Ian
    Biofabrication is the use of additive manufacturing (3D printing) for biological applications. The ultimate goal of biofabrication is to print viable organs for transplantation using patients’ own cells. In order for ...
  • BIOROW Real-Time Rowing Monitor 

    Gomez-Feria Ferreiro, Jose; Woodle, Chris
    The rower needs technical feedback that can provide information about the rowers motion. Improving rowing technique can help reduce the injuries acquired in the sport. The BIOROW model is a technique feedback system that ...
  • Analyzing Thermal and Mechanical Effects of Pulsed Laser Irradiation on Tissues 

    Ganguly, Mohit (2014-05)
    Pulsed lasers are known for their spatial and temporal specificity in delivering heat energy to the tissues. This is useful in laser ablation treatment mechanism where damage to the healthy tissues is highly undesired. ...