Browsing by Author "Pytlos, Malgorzata J."

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    • Target DNA structure plays a critical role in RAG transposition. 

      Posey, Jennifer E.; Pytlos, Malgorzata J.; Sinden, Richard R.; Roth, David B. (2006-11)
      Antigen receptor gene rearrangements are initiated by the RAG1/2 protein complex, which recognizes specific DNA sequences termed RSS (recombination signal sequences). The RAG recombinase can also catalyze transposition: ...